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Ponalrestat [CAS 72702-95-5]

Ponalrestat [CAS 72702-95-5]

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SKU:QM-0112257-01

£59.16 GBP
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  • Description

    Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM) . Ponalrestat inhibits the conversion of glucose to sorbitol[1][2][3].

  • CAS Number

    [72702-95-5]

  • Molecular Formula

    C17H12BrFN2O3

  • Molecular Weight

    391.19

  • Smiles

    OC(CC(C1=C2C=CC=C1)=NN(CC3=C(C=C(Br)C=C3)F)C2=O)=O

  • Target

    Aldose Reductase

  • Concentration

    10mM

  • Purity

    99.51

  • Solubility

    DMSO : 62.5 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0112257-01
5 mgQM-0112257-01
£59.16/ea
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10 mgQM-0112257-02
10 mgQM-0112257-02
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10 mM - 1 mLQM-0112257-03
10 mM - 1 mLQM-0112257-03
£89.13/ea
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£89.13/ea £0.00
50 mgQM-0112257-04
50 mgQM-0112257-04
£188.51/ea
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100 mgQM-0112257-05
100 mgQM-0112257-05
£282.06/ea
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Ponalrestat [CAS 72702-95-5]

Ponalrestat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.