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Pradigastat [CAS 956136-95-1]

Pradigastat [CAS 956136-95-1]

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QM-0153445-01

£351.32 GBP
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Product Details

  • Description

    Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro[1][2][3][4].

  • CAS Number

    [956136-95-1]

  • Molecular Formula

    C25H24F3N3O2

  • Molecular Weight

    455.47

  • Smiles

    O=C(O)C[C@H]1CC[C@H](C2=CC=C(C3=NC=C(NC4=CC=C(C(F)(F)F)N=C4)C=C3)C=C2)CC1

  • Target

    Acyltransferase; BCRP; OAT

  • Purity

    99.59

  • Solubility

    DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0153445-01
5 mgQM-0153445-01
£351.32/ea		 £0.00
£351.32/ea £0.00
10 mM - 1 mLQM-0153445-02
10 mM - 1 mLQM-0153445-02
£381.69/ea		 £0.00
£381.69/ea £0.00
10 mgQM-0153445-03
10 mgQM-0153445-03
£514.13/ea		 £0.00
£514.13/ea £0.00
50 mgQM-0153445-04
50 mgQM-0153445-04
£1,179.95/ea		 £0.00
£1,179.95/ea £0.00
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Pradigastat [CAS 956136-95-1]

Pradigastat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.