Prinomastat [CAS 192329-42-3]
Prinomastat [CAS 192329-42-3]
SKU:QM-0140330-01
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Product Details
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Description
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity[1][2][3][4].
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CAS Number
[192329-42-3]
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Molecular Formula
C18H21N3O5S2
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Molecular Weight
423.51
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Smiles
O=C([C@@H]1N(S(=O)(C2=CC=C(OC3=CC=NC=C3)C=C2)=O)CCSC1(C)C)NO
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Target
Apoptosis; MMP
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Isoform
MMP-1; MMP-13; MMP-2; MMP-3; MMP-9
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Purity
99.27
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Solubility
1 M HCl : 25 mg/mL (ultrasonic) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 2.5 mg/mL (ultrasonic; adjust pH to 3 with HCl)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H360
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Precautions
H360
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Prinomastat [CAS 192329-42-3]
Prinomastat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.