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PROTAC EGFR degrader 10 [CAS 3034244-56-6]
PROTAC EGFR degrader 10 [CAS 3034244-56-6]
SKU:QM-0114574
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Product Details
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Description
PROTAC EGFR degrader 10 (Compound B56) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 Ki of 37 nM. PROTAC EGFR degrader 10 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 [1].
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CAS Number
[3034244-56-6]
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Molecular Formula
C49H65ClN10O7S
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Molecular Weight
973.62
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Smiles
O=C1C(C2=CC=C(N3CCC(OCCN(CC4)CCN4C(CC5)CCN5C(C(CC)=C6)=CC(OC)=C6NC7=NC=C(Cl)C(NC8=CC=C(OC)C=C8N(S(=O)(C)=O)C)=N7)CC3)C=C2)CCC(N1)=O
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Target
EGFR; FAK; PROTACs
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Isoform
Cereblon
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Shipping Conditions
Room temperature
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PROTAC EGFR degrader 10 [CAS 3034244-56-6]
PROTAC EGFR degrader 10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.