PROTAC EGFR degrader 3 [CAS 2768472-28-0]
PROTAC EGFR degrader 3 [CAS 2768472-28-0]
SKU:QM-0148300-01
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Product Details
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Description
PROTAC EGFR degrader 3 is a potent PROTAC EGFR degrader. PROTAC EGFR degrader 3 shows excellent cellular activity against the H1975 and HCC827 cells with high selectively. PROTAC EGFR degrader 3 shows that the lysosome is involved in the degradation process of EGFR mutant degradation[1].
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CAS Number
[2768472-28-0]
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Molecular Formula
C60H77N13O5S
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Molecular Weight
1092.4
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Smiles
C=CC(N1CCC[C@@H](C1)N2C3=C(N=C2NC4=CC=CC=C4)C=NC(NC5=CC=C(C=C5)N6CCN(CC6)CCCCCCCC(N[C@H](C(N7[C@@H](C[C@H](C7)O)C(N[C@H](C8=CC=C(C=C8)C9=C(N=CS9)C)C)=O)=O)C(C)(C)C)=O)=N3)=O
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Target
EGFR; PROTACs
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Purity
97.39
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Room Temperature
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PROTAC EGFR degrader 3 [CAS 2768472-28-0]
PROTAC EGFR degrader 3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.