PROTAC STAT3 degrader-2 [CAS 2429877-78-9]
PROTAC STAT3 degrader-2 [CAS 2429877-78-9]
SKU:QM-0070471
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Product Details
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Description
PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research[1]. PROTAC STAT3 degrader-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[2429877-78-9]
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Molecular Formula
C59H60F2N9O13P
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Molecular Weight
1172.13
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Smiles
O=C1C2=C(C#CCCCCCC(N3C[C@@H](C(N4[C@@](CC[C@H]4C(N[C@@H](CCC(N)=O)C(NC(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O)([H])CC3)=O)NC(C7=CC8=CC(C(F)(F)P(O)(O)=O)=CC=C8N7)=O)=O)C=CC=C2C(N1C9C(NC(CC9)=O)=O)=O
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Target
PROTACs; STAT
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Isoform
STAT3
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Purity
99.83
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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PROTAC STAT3 degrader-2 [CAS 2429877-78-9]
PROTAC STAT3 degrader-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.