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Proteasome-IN-6 [CAS 3063720-23-7]
Proteasome-IN-6 [CAS 3063720-23-7]
SKU:QM-0009250
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Product Details
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Description
Proteasome-IN-6 (Compound J-80) inhibits the β5 catalytic subunit of the Trypanosoma brucei 20S proteasome, inibits T. b. brucei, T. b. gambiense and T. b. rhodesiense with EC50s of 157 nM, 220 nM and 156 nM, respectively. Proteasome-IN-6 exhibits antitrypanosomal activity in mouse model[1].
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CAS Number
[3063720-23-7]
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Molecular Formula
C35H45F3N4O6
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Molecular Weight
674.75
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Smiles
CCCCCC(N[C@H](CC(N(CC)CC)=O)C(N[C@@H](CC1=CC=C(F)C=C1)C(N[C@@H](CC2=CC=C(F)C=C2F)C([C@@]3(C)CO3)=O)=O)=O)=O
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Target
Parasite; Proteasome
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Shipping Conditions
Room temperature
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Proteasome-IN-6 [CAS 3063720-23-7]
Proteasome-IN-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.