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Purfalcamine [CAS 1038620-68-6]
Purfalcamine [CAS 1038620-68-6]
SKU:QM-0139053-01
£614.98 GBP
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Product Details
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Description
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage[1][2].
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CAS Number
[1038620-68-6]
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Molecular Formula
C29H33FN8O
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Molecular Weight
528.62
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Smiles
O=C(C1=CC=C(NC2=C3N=CN(C4=CC=CC(F)=C4)C3=NC(N[C@H]5CC[C@H](N)CC5)=N2)C=C1)N6CCCCC6
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Target
Parasite
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Isoform
Plasmodium; Toxoplasma
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Purity
99.44
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Solubility
DMSO : 12.5 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Purfalcamine [CAS 1038620-68-6]
Purfalcamine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.