Purinostat (mesylate) [CAS 2650188-32-0]
Purinostat (mesylate) [CAS 2650188-32-0]
SKU:QM-0150225-01
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Product Details
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Description
Purinostat mesylate is a selective inhibitor of HDAC. Purinostat mesylate inhibits class I and class IIb HDACs with IC50s from 0.81 to 11.5 nM. Purinostat mesylate induces apoptosis and affects cell cycle of LAMA84 and 188 BL-2 cells, and shows potently anti-leukemia effects in vivo. Purinostat mesylate can be used for the research of lymphoblastic leukemia[1].
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CAS Number
[2650188-32-0]
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Molecular Formula
C24H30N10O6S
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Molecular Weight
586.62
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Smiles
O=C(C1=CN=C(N(CC2=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C3N2C)C)N=C1)NO.O=S(O)(C)=O
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Target
Apoptosis; HDAC
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Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9
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Purity
99.45
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Solubility
DMSO : 35 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Purinostat (mesylate) [CAS 2650188-32-0]
Purinostat (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.