Pyridostatin [CAS 1085412-37-8]
Pyridostatin [CAS 1085412-37-8]
SKU:QM-0000537-01
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Product Details
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Description
Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
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CAS Number
[1085412-37-8]
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Molecular Formula
C31H32N8O5
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Molecular Weight
596.64
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Smiles
O=C(C1=CC(OCCN)=CC(C(NC2=NC3=C(C(OCCN)=C2)C=CC=C3)=O)=N1)NC4=CC(OCCN)=C5C=CC=CC5=N4
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Target
G-quadruplex
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Purity
96.03
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Solubility
DMSO : 100 mg/mL
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Pyridostatin [CAS 1085412-37-8]
Pyridostatin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.