Pyridostatin (hydrochloride) [CAS 1781882-65-2]
Pyridostatin (hydrochloride) [CAS 1781882-65-2]
SKU:QM-0150645-01
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Product Details
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Description
Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
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CAS Number
[1781882-65-2]
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Molecular Formula
C31H37Cl5N8O5
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Molecular Weight
778.94
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Smiles
O=C(C1=CC(OCCN)=CC(C(NC2=NC3=C(C(OCCN)=C2)C=CC=C3)=O)=N1)NC4=CC(OCCN)=C5C=CC=CC5=N4.Cl.Cl.Cl.Cl.Cl
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Target
G-quadruplex
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Purity
99.95
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Solubility
H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Pyridostatin (hydrochloride) [CAS 1781882-65-2]
Pyridostatin (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.