Pyridostatin (TFA) [CAS 1472611-44-1]
Pyridostatin (TFA) [CAS 1472611-44-1]
SKU:QM-0150646-01
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Product Details
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Description
Pyridostatin (RR82) TFA is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin TFA promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin TFA targets the proto-oncogene Src. Pyridostatin TFA reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2][3].
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CAS Number
[1472611-44-1]
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Molecular Formula
C33H33F3N8O7
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Molecular Weight
710.66
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Smiles
O=C(C1=NC(C(NC2=NC3=CC=CC=C3C(OCCN)=C2)=O)=CC(OCCN)=C1)NC4=NC5=CC=CC=C5C(OCCN)=C4.O=C(O)C(F)(F)F
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Target
G-quadruplex
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Purity
99.54
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Solubility
H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Pyridostatin (TFA) [CAS 1472611-44-1]
Pyridostatin (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.