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Pyrimethamine [CAS 58-14-0]
Pyrimethamine [CAS 58-14-0]
SKU:QM-0154853-01
£117.25 GBP
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Product Details
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Description
Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate[1][2].
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CAS Number
[58-14-0]
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Molecular Formula
C12H13ClN4
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Molecular Weight
248.71
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Smiles
NC1=NC(N)=C(C2=CC=C(Cl)C=C2)C(CC)=N1
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Target
Antifolate; Parasite
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Isoform
Plasmodium
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Concentration
10mM
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Purity
99.99
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Solubility
DMSO : 20 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Pyrimethamine [CAS 58-14-0]
Pyrimethamine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.