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Quisinostat (hydrochloride) [CAS 1083078-98-1]
Quisinostat (hydrochloride) [CAS 1083078-98-1]
SKU:QM-0007588
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Product Details
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Description
Quisinostat (JNJ-26481585) hydrochloride is a potent and orally active pan-HDAC inhibitor (HDACi), with IC50 values ranging from 0.11 nM to 0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11. Quisinostat hydrochloride has a broad spectrum antitumoral activity. Quisinostat hydrochloride can induce autophagy in neuroblastoma cells[1][2].
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CAS Number
[1083078-98-1]
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Molecular Formula
C21H27ClN6O2
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Molecular Weight
430.93
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Smiles
O=C(NO)C1=CN=C(N=C1)N2CCC(CC2)CNCC3=CN(C4=C3C=CC=C4)C.Cl
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Target
Autophagy; HDAC
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Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC4; HDAC5; HDAC6; HDAC7; HDAC8; HDAC9
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Shipping Conditions
Room temperature
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Quisinostat (hydrochloride) [CAS 1083078-98-1]
Quisinostat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.