R 59-022 (hydrochloride) [CAS 93076-98-3]
R 59-022 (hydrochloride) [CAS 93076-98-3]
SKU:QM-0112635-01
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Product Details
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Description
R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 µM) . R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC) . R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].
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CAS Number
[93076-98-3]
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Molecular Formula
C27H27ClFN3OS
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Molecular Weight
496.04
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Smiles
O=C1C(CCN(CC/2)CCC2=C(C3=CC=CC=C3)/C4=CC=C(F)C=C4)=C(C)N=C5N1C=CS5.[H]Cl
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Target
5-HT Receptor; PKC
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Isoform
MUC4; PKC
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Purity
98.88
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302-H315-H319
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Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
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R 59-022 (hydrochloride) [CAS 93076-98-3]
R 59-022 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.