1
/
of
1
(R) -DRF053 (dihydrochloride) [CAS 1241675-76-2]
(R) -DRF053 (dihydrochloride) [CAS 1241675-76-2]
SKU:QM-0083258-01
£269.91 GBP
Quantity
Couldn't load pickup availability
Request quote or documents
![(R) -DRF053 (dihydrochloride) [CAS 1241675-76-2]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
(R) -DRF053 dihydrochloride is a potent casein kinases 1 (CK1), CDK1/cyclin B and CDK5/p25 inhibitor with IC50s of 14 nM, 220 nM and 80 nM, respectively. (R) -DRF053 dihydrochloride prevents the CK1-dependent production of amyloid-beta in a cell model[1].
-
CAS Number
[1241675-76-2]
-
Molecular Formula
C23H29Cl2N7O
-
Molecular Weight
490.43
-
Smiles
CC(C)N1C2=NC(N[C@@H](CO)CC)=NC(NC3=CC(C4=CC=CC=N4)=CC=C3)=C2N=C1.Cl.Cl
-
Target
Casein Kinase; CDK
-
Isoform
CDK1; CDK5; CK1
-
Purity
99.3
-
Solubility
DMSO : 49.04 mg/mL (ultrasonic; warming)
-
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
-
Shipping Conditions
Room Temperature
Related Products
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0051720-01 β-Phenylethyl β-D-glucoside [CAS 18997-54-1]
- QM-0049152-01 β-keto Phentermine (hydrochloride) [CAS 6946-08-3]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0022874 β-Prumycin hydrochloride [CAS 54612-74-7]
- QM-0008481-01 β-Methoxy 2C-B (hydrochloride) [CAS 98537-39-4]
- QM-0005999-01 β-Muricholic acid (Standard) [CAS 2393-59-1]
- QM-0161998-01 γ-Aminobutyric acid (Standard) [CAS 56-12-2]
Other industry favorites
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0143709-01 γ-Acetylenic GABA (hydrochloride) [CAS 103451-26-9]
- QM-0178574-01 β-Sitosterol acetate, 40% (contains Campesterol acetate) [CAS 915-05-9]
- QM-0061106-01 γ-D-Glutamylaminomethylsulfonic acid [CAS 90237-02-8]
- QM-0090052 β-Peltoboykinolic acid [CAS 24778-48-1]
- QM-0161999-01 γ-Aminobutyric acid-d6 [CAS 70607-85-1]
- QM-0162002-01 γ-Aminobutyric acid-13C4
- QM-0111443-01 β-Methylcholine (chloride) [CAS 2382-43-6]
- QM-0067514 γ-Secretase modulator 11 (hydrochloride) [CAS 2434630-30-3]
(R) -DRF053 (dihydrochloride) [CAS 1241675-76-2]
(R) -DRF053 (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.