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(R) - (-) -Gossypol acetic acid [CAS 866541-93-7]
(R) - (-) -Gossypol acetic acid [CAS 866541-93-7]
SKU:QM-0151502-01
£100.38 GBP
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Product Details
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Description
(R) - (-) -Gossypol acetic acid (AT-101 (acetic acid) ) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.
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CAS Number
[866541-93-7]
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Molecular Formula
C32H34O10
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Molecular Weight
578.61
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Smiles
OC1=C2C(C=O)=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O.CC(O)=O
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Target
Autophagy; Bcl-2 Family
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Isoform
Bcl-2; Bcl-xL; Mcl-1
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Purity
98.93
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Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Blue Ice
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(R) - (-) -Gossypol acetic acid [CAS 866541-93-7]
(R) - (-) -Gossypol acetic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.