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(R) -Thalidomide-piperazine-pyrrolidineethanol
(R) -Thalidomide-piperazine-pyrrolidineethanol
SKU:QM-0085010
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Product Details
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Description
(R) -Thalidomide-piperazine-pyrrolidineethanol is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. (R) -Thalidomide-piperazine-pyrrolidineethanol can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C24H31N5O5
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Molecular Weight
469.53
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Smiles
O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)C[C@@H]5CN(CC5)CCO)=C3)C2=O)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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(R) -Thalidomide-piperazine-pyrrolidineethanol
(R) -Thalidomide-piperazine-pyrrolidineethanol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.