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R121919 (hydrochloride) [CAS 195055-66-4]
R121919 (hydrochloride) [CAS 195055-66-4]
SKU:QM-0059039
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Product Details
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Description
R121919 (NBI30775) hydrochloride is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 hydrochloride has antidepressant and anxiolytic effects. R121919 hydrochloride alleviates defensive withdrawal in rats[1][2][3].
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CAS Number
[195055-66-4]
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Molecular Formula
C22H33ClN6
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Molecular Weight
416.99
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Smiles
CCCN(CCC)C1=CC(C)=NC2=C(C3=C(C)C=C(N(C)C)N=C3)C(C)=NN12.[H]Cl
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Target
CRFR
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Isoform
CRFR1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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R121919 (hydrochloride) [CAS 195055-66-4]
R121919 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.