Ranirestat [CAS 147254-64-6]
Ranirestat [CAS 147254-64-6]
SKU:QM-0151030-01
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Product Details
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Description
Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas[1][2].
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CAS Number
[147254-64-6]
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Molecular Formula
C17H11BrFN3O4
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Molecular Weight
420.19
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Smiles
O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O
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Target
Aldose Reductase
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Concentration
10mM
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Purity
98
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Solubility
DMSO : ≥ 50 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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Ranirestat [CAS 147254-64-6]
Ranirestat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.