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Regorafenib (Hydrochloride) [CAS 835621-07-3]

Regorafenib (Hydrochloride) [CAS 835621-07-3]

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QM-0144304-01

£65.37 GBP
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Product Details

  • Description

    Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[1].

  • CAS Number

    [835621-07-3]

  • Molecular Formula

    C21H16Cl2F4N4O3

  • Molecular Weight

    519.28

  • Smiles

    ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl

  • Target

    Autophagy; PDGFR; Raf; RET; VEGFR

  • Isoform

    B-Raf; C-Raf; PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4

  • Concentration

    10mM

  • Purity

    99.58

  • Solubility

    DMSO : ≥ 5.6 mg/mL|H2O : < 0.1 mg/mL

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302

  • Precautions

    H302
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Variant Variant total Quantity Price Variant total
5 mgQM-0144304-01
5 mgQM-0144304-01
£65.37/ea		 £0.00
£65.37/ea £0.00
10 mgQM-0144304-02
10 mgQM-0144304-02
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0144304-03
10 mM - 1 mLQM-0144304-03
£101.50/ea		 £0.00
£101.50/ea £0.00
50 mgQM-0144304-04
50 mgQM-0144304-04
£200.66/ea		 £0.00
£200.66/ea £0.00
100 mgQM-0144304-05
100 mgQM-0144304-05
£275.99/ea		 £0.00
£275.99/ea £0.00
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Regorafenib (Hydrochloride) [CAS 835621-07-3]

Regorafenib (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.