Regorafenib (monohydrate) (Standard) [CAS 1019206-88-2]
Regorafenib (monohydrate) (Standard) [CAS 1019206-88-2]
SKU:QM-0083202-01
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Product Details
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Description
Regorafenib (monohydrate) (Standard) is the analytical standard of Regorafenib (monohydrate) . This product is intended for research and analytical applications. Regorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity[1].
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CAS Number
[1019206-88-2]
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Molecular Formula
C21H17ClF4N4O4
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Molecular Weight
500.83
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Smiles
O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F.O
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Target
Autophagy; c-Kit; FGFR; PDGFR; Raf; Reference Standards; RET; Tie; VEGFR
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Shipping Conditions
Room temperature
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Regorafenib (monohydrate) (Standard) [CAS 1019206-88-2]
Regorafenib (monohydrate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.