Retinoic acid-d6 [CAS 2483831-72-5]
Retinoic acid-d6 [CAS 2483831-72-5]
SKU:QM-0066927
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Product Details
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Description
Retinoic acid-d6 is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].
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CAS Number
[2483831-72-5]
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Molecular Formula
C20H22D6O2
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Molecular Weight
306.47
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Smiles
OC(/C=C(C([2H])([2H])[2H])/C=C/C=C(C([2H])([2H])[2H])/C=C/C1=C(C)CCCC1(C)C)=O
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Target
Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; PPAR; RAR/RXR
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Purity
98.9
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H360, H410
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Precautions
H302, H315, H360, H410
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Retinoic acid-d6 [CAS 2483831-72-5]
Retinoic acid-d6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.