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ROCK/HDAC-IN-2
ROCK/HDAC-IN-2
SKU:QM-0010318
Price on request
Quantity
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Product Details
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Description
ROCK/HDAC-IN-2 (Compound C-9) is a ROCK/HDAC inhibitor, with IC50 values of 0.185 µM, 0.8 µM, and 0.7 µM for HDAC6, ROCK1, and ROCK2, respectively. ROCK/HDAC-IN-2 can induce apoptosis and changes in mitochondrial membrane potential in cancer cells, demonstrating significant antitumor activity. ROCK/HDAC-IN-2 can be used in the research of pancreatic ductal adenocarcinoma (PDAC) and triple-negative breast cancer (TNBC) [1].
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Molecular Formula
C22H32N4O4S
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Molecular Weight
448.58
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Smiles
O=C(NO)CCCCCCCN1CCCN(CC1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O
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Target
Apoptosis; HDAC; ROCK
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Isoform
HDAC6; ROCK1; ROCK2
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Shipping Conditions
Room temperature
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ROCK/HDAC-IN-2
ROCK/HDAC-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.