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Rodatristat [CAS 1673568-73-4]
Rodatristat [CAS 1673568-73-4]
SKU:QM-0139792-01
£815.45 GBP
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Product Details
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Description
Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice[1].
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CAS Number
[1673568-73-4]
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Molecular Formula
C27H27ClF3N5O3
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Molecular Weight
561.98
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Smiles
O=C([C@H]1NCC2(CCN(C3=NC(N)=NC(O[C@H](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O
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Target
5-HT Receptor; Tryptophan Hydroxylase
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Isoform
MUC4
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Purity
98.41
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Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Rodatristat [CAS 1673568-73-4]
Rodatristat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.