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Rodatristat ethyl [CAS 1673571-51-1]
Rodatristat ethyl [CAS 1673571-51-1]
SKU:QM-0079979-01
£511.70 GBP
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Product Details
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Description
Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) [1][2].
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CAS Number
[1673571-51-1]
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Molecular Formula
C29H31ClF3N5O3
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Molecular Weight
590.04
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Smiles
ClC1=CC(C2=CC=CC=C2)=C([C@@H](OC3=NC(N)=NC(N4CCC5(CN[C@H](C(OCC)=O)C5)CC4)=C3)C(F)(F)F)C=C1
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Target
5-HT Receptor; Tryptophan Hydroxylase
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Isoform
MLAG-3
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Purity
98.04
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Rodatristat ethyl [CAS 1673571-51-1]
Rodatristat ethyl is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.