Ropivacaine (hydrochloride monohydrate) [CAS 132112-35-7]
Ropivacaine (hydrochloride monohydrate) [CAS 132112-35-7]
SKU:QM-0158600-01
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Product Details
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Description
Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[1][2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane[3]. Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo[1].
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CAS Number
[132112-35-7]
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Molecular Formula
C17H29ClN2O2
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Molecular Weight
328.88
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Smiles
O=C([C@H]1N(CCC)CCCC1)NC2=C(C)C=CC=C2C.O.Cl
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Target
Potassium Channel; Sodium Channel
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Concentration
10mM
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Purity
99.82
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H318
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Precautions
H318
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Ropivacaine (hydrochloride monohydrate) [CAS 132112-35-7]
Ropivacaine (hydrochloride monohydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.