Rosuvastatin-13C, d3 (sodium)
Rosuvastatin-13C, d3 (sodium)
SKU:QM-0102015
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Product Details
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Description
Rosuvastatin-13C, d3 sodium is 13C and deuterated labeled Rosuvastatin sodium. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
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Molecular Formula
C21 13CH24D3FN3NaO6S
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Molecular Weight
507.53
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Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N([13C]([2H])([2H])[2H])S(=O)(C)=O)N=C1C2=CC=C(C=C2)F
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Target
Autophagy; Bacterial; HMG-CoA Reductase (HMGCR) ; Isotope-Labeled Compounds; Potassium Channel
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Rosuvastatin-13C, d3 (sodium)
Rosuvastatin-13C, d3 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.