Rosuvastatin (Calcium) [CAS 147098-20-2]
Rosuvastatin (Calcium) [CAS 147098-20-2]
SKU:QM-0154656-01
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Product Details
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Description
Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
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CAS Number
[147098-20-2]
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Molecular Formula
C22H27Ca0.5FN3O6S
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Molecular Weight
500.57
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Smiles
O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
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Target
Autophagy; Bacterial; HMG-CoA Reductase (HMGCR) ; Potassium Channel
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Purity
99.94
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Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Rosuvastatin (Calcium) [CAS 147098-20-2]
Rosuvastatin (Calcium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.