Rosuvastatin-d6 (sodium) [CAS 2070009-41-3]
Rosuvastatin-d6 (sodium) [CAS 2070009-41-3]
SKU:QM-0000644
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Product Details
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Description
Rosuvastatin-d6 sodium is deuterium labeled Rosuvastatin sodium. Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
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CAS Number
[2070009-41-3]
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Molecular Formula
C22H21D6FN3NaO6S
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Molecular Weight
509.56
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Smiles
O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F
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Target
Autophagy; HMG-CoA Reductase (HMGCR)
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Purity
98.6
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302
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Precautions
H302
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Rosuvastatin-d6 (sodium) [CAS 2070009-41-3]
Rosuvastatin-d6 (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.