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RSL3 (Standard) [CAS 1219810-16-8]

RSL3 (Standard) [CAS 1219810-16-8]

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SKU:QM-0001730

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  • Description

    RSL3 (Standard) is the analytical standard of RSL3. This product is intended for research and analytical applications. RSL3 ((1S,3R) -RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1].

  • CAS Number

    [1219810-16-8]

  • Molecular Formula

    C23H21ClN2O5

  • Molecular Weight

    440.88

  • Smiles

    O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC

  • Target

    Ferroptosis; Glutathione Peroxidase; p62; Reactive Oxygen Species (ROS) ; Reference Standards

  • Shipping Conditions

    Room temperature

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RSL3 (Standard) [CAS 1219810-16-8]

RSL3 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.