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Rucaparib (hydrochloride) [CAS 773059-19-1]
Rucaparib (hydrochloride) [CAS 773059-19-1]
SKU:QM-0057584
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Product Details
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Description
Rucaparib (AG014699) hydrochloride is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib hydrochloride is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib hydrochloride has the potential for castration-resistant prostate cancer (CRPC) research[1][2][3][4].
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CAS Number
[773059-19-1]
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Molecular Formula
C19H19ClFN3O
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Molecular Weight
359.83
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Smiles
FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1.[H]Cl
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Target
PARP
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Isoform
PARP1; PARP2; PARP3
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Rucaparib (hydrochloride) [CAS 773059-19-1]
Rucaparib (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.