(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide [CAS 2248444-14-4]
(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide [CAS 2248444-14-4]
SKU:QM-0011777
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![(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide [CAS 2248444-14-4]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
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Description
(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing a key amide benzimidazole (ABZI) component and shows reproducible inhibition of 3H-cGAMP binding to STING with an apparent inhibition constant IC50 of 14 μM. (S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide can be used for tumor research[1].
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CAS Number
[2248444-14-4]
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Molecular Formula
C23H24N6O3
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Molecular Weight
432.48
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Smiles
O[C@@H](C1=CC=CC=C1)CN2C3=CC=C(C(N)=O)C=C3N=C2NC(C4=CC(C)=NN4CC)=O
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Target
STING
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Shipping Conditions
Room temperature
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(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide [CAS 2248444-14-4]
(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.