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S-Isopropylisothiourea (hydrobromide) [CAS 4269-97-0]

S-Isopropylisothiourea (hydrobromide) [CAS 4269-97-0]

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SKU:QM-0081129-01

£78.82 GBP
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  • Description

    S-Isopropylisothiourea hydrobromide (S-isopropyl ITU; IPTU) is a blood-brain barrier (BBB) penetrant NOS inhibitor with IC50 values of 0.66, 0.75 and 0.29 μM against mouse spinal cord, cerebellar, bovine aortic and porcine endothelial cell NOS. S-Isopropylisothiourea exhibits a significant blood pressure-raising effect without damaging the perfusion of vital organs and can also inhibit the late-phase pain response induced by formalin. S-Isopropylisothiourea hydrobromide is used in the researchs for hemorrhagic shock and pain response based on NOS[1][2].

  • CAS Number

    [4269-97-0]

  • Molecular Formula

    C4H11BrN2S

  • Molecular Weight

    199.11

  • Smiles

    NC(SC(C)C)=N.Br

  • Target

    NO Synthase

  • Isoform

    ENOS; nNOS

  • Purity

    98

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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S-Isopropylisothiourea (hydrobromide) [CAS 4269-97-0]

S-Isopropylisothiourea (hydrobromide) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.