(S) -PNU-282987 (hydrochloride) [CAS 128311-08-0]
(S) -PNU-282987 (hydrochloride) [CAS 128311-08-0]
SKU:QM-0060692
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Product Details
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Description
(S) -PNU-282987 hydrochloride is an isoform of PNU-282987. PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems[1].
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CAS Number
[128311-08-0]
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Molecular Formula
C14H18Cl2N2O
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Molecular Weight
301.21
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Smiles
O=C(C1=CC=C(Cl)C=C1)N[C@H]2C3CCN(CC3)C2.Cl
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Target
5-HT Receptor; nAChR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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(S) -PNU-282987 (hydrochloride) [CAS 128311-08-0]
(S) -PNU-282987 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.