(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine [CAS 2347517-69-3]
(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine [CAS 2347517-69-3]
SKU:QM-0149189-01
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Product Details
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Description
(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia. (S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine can be used for research on prostate cancer and other cancers[1][2].
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CAS Number
[2347517-69-3]
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Molecular Formula
C41H46N6O6S
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Molecular Weight
750.91
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Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCC(NC(C4=CN=CC=C4)C5=CC6=CC=CC=C6O5)=O)=O
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Target
HIF/HIF Prolyl-Hydroxylase; PROTACs; TGF-beta/Smad
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Purity
98.62
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Solubility
DMSO : ≥ 170 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine [CAS 2347517-69-3]
(S, R, S) -AHPC-C2-amide-benzofuranylmethyl-pyridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.