(S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH
(S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH
SKU:QM-0114599
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Product Details
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Description
(S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH is a conjugate of E3 ligase ligand and linker, consisting of (S, R, S) -AHPC and the corresponding Linker. (S, R, S) -AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH can be used as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C33H47N7O6S
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Molecular Weight
669.83
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Smiles
O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(CN2CC(C2)N3CCN(CC3)CC(O)=O)=O)=O)NCC(C=C4)=CC=C4C(SC=N5)=C5C
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Target
E3 Ligase Ligand-Linker Conjugates
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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(S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH
(S, R, S) -AHPC-CO-CH2-azetidine-piperazine-CH2-COOH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.