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(S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH

(S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH

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SKU:QM-0080126

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  • Description

    (S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH is a conjugate of the VHL ligand and linker of the E3 ubiquitinase VH032. The Linker of (S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH can further be linked to target protein ligands (such as BCR-ABL1) to form PROTAC molecules[1].

  • Molecular Formula

    C35H52N8O5S

  • Molecular Weight

    696.9

  • Smiles

    CC1=C(C2=CC=C([C@@H](NC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(CN4CCN(CC(N5CCNCC5)=O)CC4)=O)C(C)(C)C)=O)=O)C)C=C2)SC=N1

  • Target

    E3 Ligase Ligand-Linker Conjugates

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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(S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH

(S, R, S) -AHPC-Me-piperazine-acetyl-PIP-AcOH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.