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(S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
(S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
SKU:QM-0102566
Price on request
Quantity
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Product Details
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Description
(S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. (S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C29H36N8O6
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Molecular Weight
592.65
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Smiles
O=C1NC(CC[C@@H]1N2C(C3=C(C=CC(N4CCN(CC4)C5=NC=NC(N6CCN(CC6)CCOCCO)=C5)=C3)C2=O)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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(S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
(S) -Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.