Saikosaponin B1 [CAS 58558-08-0]
Saikosaponin B1 [CAS 58558-08-0]
SKU:QM-0162337-01
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Product Details
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Description
Saikosaponin B1 is a bioactive constituent of Radix Bupleuri. Saikosaponin B1 is an agonist of the 5-HT2C receptor with an EC50 of 147.41 μM. Saikosaponin B1 inhibits the Hedgehog (Hh) signaling pathway by targeting the transmembrane protein SMO. Sailosaponin B1 can reduce liver fibrosis. Saikosaponin B1 has anti-cancer activities thus can be studies in research for cancers such as Medulloblastoma (MB) [1][4].
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CAS Number
[58558-08-0]
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Molecular Formula
C42H68O13
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Molecular Weight
780.98
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Smiles
OC[C@@]1(C)[C@]2([H])CC[C@@]3(C)[C@]4(C)C[C@H](O)[C@@]5(CO)CCC(C)(C)CC5=C4C=C[C@]3([H])[C@@]2(C)CC[C@@H]1O[C@]6([H])O[C@H](C)[C@H](O)[C@H](O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O
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Target
Hedgehog; Interleukin Related; Smo; STAT; TNF Receptor
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Isoform
5-HT2 Receptor
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Purity
99.42
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Saikosaponin B1 [CAS 58558-08-0]
Saikosaponin B1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.