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SB 202190 (hydrochloride) [CAS 350228-36-3]

SB 202190 (hydrochloride) [CAS 350228-36-3]

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QM-0081950-01

£106.00 GBP
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Product Details

  • Description

    SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 hydrochloride has anti-cancer activity[1][2]. SB202190 hydrochloride induces autophagy[3].

  • CAS Number

    [350228-36-3]

  • Molecular Formula

    C20H15ClFN3O

  • Molecular Weight

    367.8

  • Smiles

    OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1.[H]Cl

  • Target

    Apoptosis; Autophagy; Organoid; p38 MAPK

  • Isoform

    P38α; p38β

  • Purity

    99.66

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H315, H319, H335

  • Precautions

    H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0081950-01
5 mgQM-0081950-01
£106.00/ea		 £0.00
£106.00/ea £0.00
10 mM - 1 mLQM-0081950-02
10 mM - 1 mLQM-0081950-02
£115.00/ea		 £0.00
£115.00/ea £0.00
10 mgQM-0081950-03
10 mgQM-0081950-03
£188.51/ea		 £0.00
£188.51/ea £0.00
25 mgQM-0081950-04
25 mgQM-0081950-04
£351.32/ea		 £0.00
£351.32/ea £0.00
50 mgQM-0081950-05
50 mgQM-0081950-05
£539.64/ea		 £0.00
£539.64/ea £0.00
100 mgQM-0081950-06
100 mgQM-0081950-06
£902.93/ea		 £0.00
£902.93/ea £0.00
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SB 202190 (hydrochloride) [CAS 350228-36-3]

SB 202190 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.