SB 202190 (Standard) [CAS 152121-30-7]
SB 202190 (Standard) [CAS 152121-30-7]
SKU:QM-0002571-01
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Product Details
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Description
SB 202190 (Standard) is the analytical standard of SB 202190. This product is intended for research and analytical applications. SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3].
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CAS Number
[152121-30-7]
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Molecular Formula
C20H14FN3O
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Molecular Weight
331.34
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Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1
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Target
Apoptosis; Autophagy; Organoid; p38 MAPK; Reference Standards
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Shipping Conditions
Room temperature
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SB 202190 (Standard) [CAS 152121-30-7]
SB 202190 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.