SB 242084 (monohydrochloride) [CAS 1260505-34-7]
SB 242084 (monohydrochloride) [CAS 1260505-34-7]
SKU:QM-0111250
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Product Details
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Description
SB 242084 monohydrochloride is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier) . SB 242084 monohydrochloride increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 monohydrochloride has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage[1][2][3].
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CAS Number
[1260505-34-7]
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Molecular Formula
C21H20Cl2N4O2
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Molecular Weight
431.32
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Smiles
O=C(N1CCC2=C1C=C(Cl)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl
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Target
5-HT Receptor
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Isoform
5-HT2 Receptor
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P280-P302+P352
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SB 242084 (monohydrochloride) [CAS 1260505-34-7]
SB 242084 (monohydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.