SB 271046 (Hydrochloride) [CAS 209481-24-3]
SB 271046 (Hydrochloride) [CAS 209481-24-3]
SKU:QM-0147944-01
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Product Details
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Description
SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM) [1].
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CAS Number
[209481-24-3]
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Molecular Formula
C20H23Cl2N3O3S2
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Molecular Weight
488.45
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Smiles
ClC1=CC2=C(C=C1)SC(S(=O)(NC3=CC=C(C(N4CCNCC4)=C3)OC)=O)=C2C.[H]Cl
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Target
5-HT Receptor
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Isoform
5-HT6 Receptor; Apolipoprotein D; mLAG-3; MUC2; MUC3; α-1 microglobulin
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Concentration
10mM
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Purity
99.93
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Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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SB 271046 (Hydrochloride) [CAS 209481-24-3]
SB 271046 (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.