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Secalonic acid D [CAS 35287-69-5]
Secalonic acid D [CAS 35287-69-5]
SKU:QM-0106130
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Product Details
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Description
Secalonic acid D is a toxic compound against tumor cells. Secalonic acid D can be isolated from the metabolites of Aspergillus aculeatus. Secalonic acid D activates GSK3-β, and degrades β-catenin. Thus, Secalonic acid D down-regulates c-Myc expression, arrests cell cycle at G1 phase, induces cell apoptosis[1][2].
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CAS Number
[35287-69-5]
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Molecular Formula
C32H30O14
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Molecular Weight
638.57
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Smiles
COC([C@]12C(C(C3=C(O)C(C4=CC=C(O[C@@]5(C(C6=O)=C(C[C@@H]([C@H]5O)C)O)C(OC)=O)C6=C4O)=CC=C3O1)=O)=C(C[C@@H]([C@H]2O)C)O)=O
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Target
Apoptosis; c-Myc; GSK-3; β-catenin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Secalonic acid D [CAS 35287-69-5]
Secalonic acid D is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.