Seclidemstat (mesylate) [CAS 2044953-70-8]
Seclidemstat (mesylate) [CAS 2044953-70-8]
SKU:QM-0083500-01
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Product Details
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Description
Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor (Ki=31 nM, IC50=13 nM) . Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate can be used for the research of Ewing Sarcoma[1][2].
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CAS Number
[2044953-70-8]
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Molecular Formula
C21H27ClN4O7S2
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Molecular Weight
547.04
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Smiles
O=C(N/N=C(C1=CC(Cl)=CC=C1O)\C)C2=CC=CC(S(=O)(N3CCN(C)CC3)=O)=C2.CS(O)(=O)=O
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Target
Histone Demethylase
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Isoform
KDM1/LSD1
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Purity
99.8
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Solubility
DMSO : 53.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Seclidemstat (mesylate) [CAS 2044953-70-8]
Seclidemstat (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.