Selonsertib (hydrochloride) [CAS 1448428-05-4]
Selonsertib (hydrochloride) [CAS 1448428-05-4]
SKU:QM-0118319
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Product Details
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Description
Selonsertib hydrochloride (GS-4997 hydrochloride) is an orally bioavailable enzyme inhibitor with potential anti-inflammatory, anti-tumor and anti-fibrotic activities. Selonsertib hydrochloride blocks ASK1 phosphorylation and activation by binding to the catalytic kinase domain. Selonsertib hydrochloride prevents the production of inflammatory cytokines and reduces the expression of genes associated with fibrosis. Selonsertib hydrochloride inhibits excessive apoptosis and limits cell proliferation[1].
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CAS Number
[1448428-05-4]
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Molecular Formula
C24H25ClFN7O
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Molecular Weight
481.95
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Smiles
O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F.Cl
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Target
Apoptosis; MAP3K
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Shipping Conditions
Room temperature
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Selonsertib (hydrochloride) [CAS 1448428-05-4]
Selonsertib (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.