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Semagacestat [CAS 425386-60-3]

Semagacestat [CAS 425386-60-3]

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QM-0079083-01

£90.25 GBP
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Product Details

  • Description

    Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid (Aβ42), Aβ38 and Aβ40 with IC50s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's disease[1].

  • CAS Number

    [425386-60-3]

  • Molecular Formula

    C19H27N3O4

  • Molecular Weight

    361.44

  • Smiles

    O=C([C@H]1NC([C@@H](NC([C@H](C(C)C)O)=O)C)=O)N(CCC2=C1C=CC=C2)C

  • Target

    Amyloid-β; Notch; γ-secretase

  • Purity

    99.56

  • Solubility

    DMSO : ≥ 100 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
10 mM - 1 mLQM-0079083-01
10 mM - 1 mLQM-0079083-01
£90.25/ea		 £0.00
£90.25/ea £0.00
5 mgQM-0079083-02
5 mgQM-0079083-02
£106.00/ea		 £0.00
£106.00/ea £0.00
10 mgQM-0079083-03
10 mgQM-0079083-03
£212.81/ea		 £0.00
£212.81/ea £0.00
50 mgQM-0079083-04
50 mgQM-0079083-04
£577.31/ea		 £0.00
£577.31/ea £0.00
100 mgQM-0079083-05
100 mgQM-0079083-05
£878.63/ea		 £0.00
£878.63/ea £0.00
500 mgQM-0079083-06
500 mgQM-0079083-06
£2,371.86/ea		 £0.00
£2,371.86/ea £0.00
1 gQM-0079083-07
1 gQM-0079083-07
£3,753.32/ea		 £0.00
£3,753.32/ea £0.00
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Semagacestat [CAS 425386-60-3]

Semagacestat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.