(Ser8) -GLP-1 (7-36) amide, human [CAS 215777-46-1]
(Ser8) -GLP-1 (7-36) amide, human [CAS 215777-46-1]
SKU:QM-0204699-01
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Product Details
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Description
(Ser8) -GLP-1 (7-36) amide, human is a glucagon-like peptide 1 amide derived from glucagonogen, a cleavage product of the GLP-1 (1-36) amide peptide. (Ser8) -GLP-1 (7-36) amide, human is an entero-insulinotropic hormone that causes glucose-dependent release of insulin from pancreatic β-cells and affects gastrointestinal motility and secretion[1].
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CAS Number
[215777-46-1]
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Molecular Formula
C149H226N40O46
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Molecular Weight
3313.63
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Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CCCNC(=N)N)C(N)=O)=O)=O)CCCCN)=O)C(C)C)=O)CC(C)C)=O)NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)N)=O)CO)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)=O)[C@@H](C)O)=O)CO)=O)CC(O)=O)=O)[C@H](C)C)=O)CO)=O)CO)=O)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)CCCCN)=O)CCC(O)=O)=O)=O)[C@H](CC)C)=O)C)=O)C=5C=6C(NC5)=CC=CC6
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Target
GCGR
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Purity
99.1
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Solubility
10 mM in DMSO
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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(Ser8) -GLP-1 (7-36) amide, human [CAS 215777-46-1]
(Ser8)-GLP-1 (7-36) amide, human (CAS 215777-46-1) is a certified peptide reference standard supplied by Quantimol for laboratory and scientific research.
This compound is a Ser8-substituted analogue of GLP-1 (7-36) amide, a glucagon-like peptide derived from proglucagon. It is an entero-insulinotropic hormone that stimulates glucose-dependent insulin release from pancreatic β-cells and modulates gastrointestinal motility and secretion. The Ser8 substitution confers resistance to DPP-IV cleavage, extending its biological half-life compared to native GLP-1.
Key properties:
- Peptide class: GLP-1 analogue (incretin)
- CAS Number: 215777-46-1
- Target: GLP-1 receptor (GLP1R)
- Modification: Ser8 substitution (DPP-IV resistant)
- Purity: ≥95% (HPLC)
- Storage: -20°C, protected from light
- Solubility: Water or PBS (recommended)
Applications: Incretin biology, insulin secretion studies, GLP-1 receptor pharmacology, diabetes and obesity research, GI motility research.
Supplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.