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Simvastatin acid (calcium hydrate) [CAS 530112-57-3]

Simvastatin acid (calcium hydrate) [CAS 530112-57-3]

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SKU:QM-0139687-01

£248.04 GBP
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  • Description

    Simvastatin acid (Tenivastatin) calcium hydrate is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid calcium hydrate reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid calcium hydrate can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].

  • CAS Number

    [530112-57-3]

  • Molecular Formula

    C25H40O6.1/2Ca.xH2O

  • Smiles

    CCC(C)(C)C(O[C@@H]1[C@@]2([H])C(C=C[C@@H]([C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)C)=C[C@@H](C1)C)=O.[1/2Ca].[xH2O]

  • Target

    HMG-CoA Reductase (HMGCR) ; Reactive Oxygen Species (ROS)

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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5 mgQM-0139687-02
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Simvastatin acid (calcium hydrate) [CAS 530112-57-3]

Simvastatin acid (calcium hydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.